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Phylophenetic properties of metabolic pathway topologies as revealed by global analysis
Authors:Yong Zhang  Shaojuan Li  Geir Skogerbø  Zhihua Zhang  Xiaopeng Zhu  Zefeng Zhang  Shiwei Sun  Hongchao Lu  Baochen Shi  Runsheng Chen
Institution:(1) Bioinformatics Laboratory and National Laboratory of Bromacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China;(2) Bioinformatics Research Group, Key Laboratory of Intelligent Information Processing, Institute of Computing Technology, Beijing, 100080, China;(3) Graduate School of the Chinese Academy of Sciences, Beijing, China
Abstract:

Background  

As phenotypic features derived from heritable characters, the topologies of metabolic pathways contain both phylogenetic and phenetic components. In the post-genomic era, it is possible to measure the "phylophenetic" contents of different pathways topologies from a global perspective.
Keywords:
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