Cytogenetic analysis of thioTEPA-induced translocations in the spermatids of male mice

Spermatocytes of 36 reciprocal translocation heterozygotes at diakinesis-MI stage were studied cytogenetically. There were 38.8 % cells with rings and 32.8 % - with chains and univalents among 3666 cells. It is concluded that intensive mutational process producing 30 % of translocation heterozygotes is characterized by random breakage along the chromosomes.