Chiral Pool‐Based Synthesis of Naphtho‐Fused Isocoumarins |
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| Authors: | Abdul Rauf Raza Aisha Saddiqa Osman Çakmak |
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| Institution: | 1. Ibn e Sina Block, Department of Chemistry, University of Sargodha, Sargodha, Pakistan;2. Department of Chemistry, Faculty of Art and Science, Y?ld?z Technical University, ?stanbul, Turkey |
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| Abstract: | A variety of chiral derivatives of benzod]naphtho1,2‐b]pyran‐6‐one were prepared in a single step by Et3N‐mediated condensation of homophthalic anhydride with different derivatives of (S)‐amino acid chlorides at –5 °C by employing a chiral pool methodology. Chirality 27:951–957, 2015. © 2015 Wiley Periodicals, Inc. |
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| Keywords: | isocoumarin benzo[d]naphtho[1 2‐b]pyran‐6‐one homophthalic anhydride amino acids |
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