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Estimating and reducing bias in group sequential designs with Gaussian independent increment structure
Authors:PINHEIRO  JOSE C; DEMETS  DAVID L
Institution:Bell Laboratories, Lucent Technologies Murray Hill, New Jersey 07974-2070, U.S.A. e-mail: jcp{at}bell-labs.com
Department of Biostatistics, University of Wisconsin-Madison Madison, Wisconsin 53706, U.S.A. e-mail: demets{at}biostat.wisc.edu
Abstract:
Keywords:Alpha-spending method  Clinical trial  Estimation  Group sequential test
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