Ly-5: A new T-lymphocyte antigen system |
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| Authors: | K Komuro K Itakura E A Boyse M John |
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| Institution: | (1) Memorial Sloan-Kettering Cancer Center, 10021 New York, N.Y. |
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| Abstract: | Ly-5 is a third genetic locus of the type so far represented in the mouse byLy-1 andLy-2/Ly-3; it specifies antithetical alloantigens, one of which is present exclusively on T lymphocytes of every mouse. The chromosomal locus ofLy-5 has not been established, but it is not closely linked toLy-1 orLy-2/Ly-3. Like other T-lymphocyte surface markers, expression of Ly-5 antigens on T-lymphocyte precursor cells can be initiated in vitro by inducers of T-cell differentiation.Recipient of a fellowship from the New York Cancer Research Institute, Inc. |
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