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Lanostanes and friedolanostanes from the pericarp of Garcinia hombroniana
Authors:Rukachaisirikul V  Adair A  Dampawan P  Taylor W C  Turner P C
Institution:Department of Chemistry, Faculty of Science, Prince of Songkhla University, Hat Yai, Thailand. rvatchar@ratree.psu.ac.th
Abstract:The CH2Cl2 extract from the pericarp of Garcinia hombroniana yielded three 17,14-friedolanostanes (24E)-3alpha-hydroxy-17,14-friedolanostan-8, 14,24-trien-26-oic acid, methyl (24E)-3alpha,23-dihydroxy-17,14-friedolanostan-8,14,24 -trien-26-oate and methyl (24E)-3alpha,9,23-trihydroxy-17,14-friedolanostan-14,2 4-dien-26-oate] and two lanostanes 3beta- and 3alpha-hydroxy-23-oxo-9,16-lanostadien-26-oic acid]. The structure of (14E)-3alpha-hydroxy-17,14-friedolanostan-8,14,24-trie n-26-oic acid was determined using spectroscopic and X-ray analyses, while the structures of the other compounds were elucidated solely from analysis of spectroscopic data.
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