The Russian Gene Pool: Frequencies of Genetic Markers |
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| Authors: | Spitsyn V A Kuchheuser W Makarov S V Bychkovskaya L S Pai G V Balanovskii O P Afanas'eva I S |
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| Institution: | (1) Medical Genetic Research Center, Russian Academy of Medical Sciences, Moscow, 115478, Russia;(2) Institute of Forensic Medicine, Magdeburg University, Magdeburg, D-39120, Germany |
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| Abstract: | Frequency distribution of several genetic markers was studied in ethnic Russians from the Moscow, Bryansk, Ryazan', Kostroma, Novgorod, Arkhangel'sk, and Sverdlovsk oblasts and Udmurtiya. Systems AB0, RH, HP, TF, GC, PI, C"3, ACP1, PGM1, ESD, GLO1, 6PGD, and AK were analyzed in most samples. New data on informative polymorphic genetic loci showed that the Russian gene pool mostly displays Caucasoid features. Some data on polymorphism of nuclear genome loci are presented. In addition, Y-chromosomal short tandem repeats (STRs) DYS19, DYS390, and DYCAIIwere analyzed in the Russian samples. STRs of the chromosome are particularly valuable for elucidating ethnogenetic processes in Eastern Europe. Frequency distributions of the Y-chromosomal markers in Russians were intermediate between those of West European populations and eastern Finno-Ugric ethnoses of the Volga region. A marked longitudinal gradient was revealed for frequencies of several molecular markers. |
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