Intracytoplasmic desmosomes in tumor cells |
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| Affiliation: | 1. Department of Anatomy, University of Hong Kong Hong Kong;2. Institute of Radiology and Oncology, Medical and Health Department, Queen Elizabeth Hospital, Kowloon, Hong Kong;1. Division of Nephrology, Shanghai Changzheng Hospital, Second Military Medical University (Naval Medical University), Shanghai, China;2. Outpatient Department, Yangpu Third Military Retreat, Shanghai, China;3. Department of Nephrology and Endocrinology, Shanghai 411 Hospital, Shanghai, China;4. Department of Nephrology, Zhabei Central Hospital of JingAn District of Shanghai, Shanghai, China;1. Division of Nephrology, Department of Internal Medicine, Daejeon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Jung-gu, Daejeon, Republic of Korea;2. Division of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan |
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| Abstract: | The occurrence of intracytoplasmic desmosomes in some normal and tumor cells was suggested to develop by cell fusion by previous investigators. In this study, similar structures were found in tumor biopsies and tumor cells in culture. It is suggested that these structures develop by membrane incorporation and dissolution in cells with active membrane turnover. |
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