Mixed infections with Chlamydia and porcine epidemic diarrhea virus - a new in vitro model of chlamydial persistence |
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| Authors: | Nicole Borel Claudia Dumrese Urs Ziegler Andrea Schifferli Carmen Kaiser Andreas Pospischil |
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| Affiliation: | (1) Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland;(2) Center for Microscopy and Image Analysis, University of Zurich, Zurich, Switzerland |
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| Abstract: | Background Chlamydiae induce persistent infections, which have been associated with a wide range of chronic diseases in humans and animals. Mixed infections with Chlamydia and porcine epidemic diarrhea virus (PEDV) may result in generation of persistent chlamydial infections. To test this hypothesis, an in vitro model of dual infection with cell culture-adapted PEDV and Chlamydia abortus or Chlamydia pecorum in Vero cells was established. |
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