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The endogenous production of hydrogen sulphide in intrauterine tissues |
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| Authors: | Pushpa Patel Manu Vatish John Heptinstall Rui Wang Ray J Carson |
| Affiliation: | (1) College of Medical & Dental Sciences, University of Birmingham, Birmingham, UK;(2) Molecular Medicine Research Group, University of Warwick, Coventry, UK;(3) Biomolecular Sciences Dept., Coventry University, Coventry, UK;(4) Department of Biology, Lakehead University, Thunder Bay, Ontario, Canada;(5) Dept of Medical & Social Care Education, School of Medicine, University of Leicester, Leicester, UK |
| Abstract: | BackgroundHydrogen sulphide is a gas signalling molecule which is produced endogenously from L-cysteine via the enzymes cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE). The possible role of hydrogen sulphide in reproduction has not yet been fully investigated. It has been previously demonstrated that hydrogen sulphide relaxes uterine smooth muscle in vitro. The aim of the present study was to investigate the endogenous production of hydrogen sulphide in rat and human intrauterine tissues in vitro. |
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