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Global human genetics of HIV-1 infection and China
Authors:Tuo Fu ZHU Tie Jian FENG Xin XIAO Hui WANG Bo Ping ZHOU
Affiliation:Departments of Laboratory Medicine, University of Washington School of Medicine, Seattle, WA 98195-8070, USA;Departments of Microbiology, University of Washington School of Medicine, Seattle, WA 98195-8070, USA;Programs in Infectious Diseases, Fred Hutchinson Cancer Research Center, Seattle, WA 98195-8070, USA Shenzhen Center for Disease Control and Prevention, Shenzhen, China Department of Neonatology, Perinatal Medicine Center, Medical College of Jinan University, Guangzhou, China Shenzhen Municipal Hospital of Infectious Diseases, Shenzhen, China Shenzhen Municipal Hospital of Infectious Diseases, Shenzhen, China
Abstract:Genetic polymorphisms in human genes can influence the risk for HIV-1 infection and disease progression, although the reported effects of these alleles have been inconsistent. This review highlights the recent discoveries on global and Chinese genetic polymorphisms and their association with HIV-1 transmission and disease progression.
Keywords:HIV   genetic polymorphisms   China.
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