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Platelet membrane Ca(2+) and Na(+), K(+)-ATPase activity and aggregation in myelodysplastic syndrome
Authors:Bielins'ka I V  Ostrovs'ka H V  Rybal'chenko V K  Koval'chuk T O  Klymenko V I
Affiliation:Taras Shevchenko Kyiv National University, Ukraine.
Abstract:Platelet aggregation was decreased under action of ADP and collagen in patients with myelodysplastic syndrome. The decrease in aggregation started from 3-rd minutes and decreased in 4 and 5 minutes after action of ADP. The study of Ca(2+)-ATPase and Na+, K(+)-ATPase membrane activities showed the decrease in Ca(2+)-ATPase and increase in Na+, K(+)-ATPase activity in the patients with myelodysplastic syndrome.
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