Platelet membrane Ca(2+) and Na(+), K(+)-ATPase activity and aggregation in myelodysplastic syndrome |
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Authors: | Bielins'ka I V Ostrovs'ka H V Rybal'chenko V K Koval'chuk T O Klymenko V I |
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Affiliation: | Taras Shevchenko Kyiv National University, Ukraine. |
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Abstract: | Platelet aggregation was decreased under action of ADP and collagen in patients with myelodysplastic syndrome. The decrease in aggregation started from 3-rd minutes and decreased in 4 and 5 minutes after action of ADP. The study of Ca(2+)-ATPase and Na+, K(+)-ATPase membrane activities showed the decrease in Ca(2+)-ATPase and increase in Na+, K(+)-ATPase activity in the patients with myelodysplastic syndrome. |
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