巨细胞病毒感染与细胞内钙离子变化相关性研究

人类受人巨细胞病毒（HCMV）感染非常普遍，但其致病机制尚不清楚，钙是细胞内最普遍而重要的信号传导成分，它在细胞活动的各种生理生化反应和疾病的发生和发展中有重要作用，HCMV感染后对受染细胞内钙离子浓度产生明显影响，这不仅有利于HCMV在胞内的复制和成熟，而且与其致病有关。

Study of correlation between cytomegalovirus infection and the changes of intracellular [Ca2+] concentration

Human cytornegalovirus (HCMV) infection is very common in human being, but the mechanisms of causing damage is understood poorly. Calcium is the most important component in the process of intracellular signal transduction. Also, calcium plays a important role in a series of intracellular reaction of physiology and biochemistry and the occurrence and development of diseases. HCMV infection can significantly affect intracellular [Ca2+] concentration of infected cells, which are not only favor to the replication and maturation of intracellular viruses, but the pathogenicity.