|
|||||
|
|
Resources for genetic management and genomics research on non-human primates at the National Primate Research Centers (NPRCs) |
|
| Authors: | S. Kanthaswamy,J.P. Capitanio,C.J. Dubay,B. Ferguson,T. Folks,J.C. Ha,C.E. Hotchkiss,Z.P. Johnson,M.G. Katze,L.S. Kean,H. Michael Kubisch,S. Lank,L.A. Lyons,G.M. Miller,J. Nylander,D.H. O'Connor,R.E. Palermo,D.G. Smith,E.J. Vallender,R.W. Wiseman,& J. Rogers |
| Affiliation: | Department of Anthropology, University of California–Davis, CA, USA; California National Primate Research Center, University of California–Davis, CA, USA; Department of Psychology, University of California–Davis, CA, USA; Department of Molecular Medical Genetics, Oregon Health and Science University, Portland, OR, USA; Primate Genetics Program, Oregon National Primate Research Center, Oregon Health and Sciences University, Beaverton, OR, USA; Southwest National Primate Research Center, San Antonio, TX, USA; Psychology Department, University of Washington, Seattle, WA, USA; Washington National Primate Research Center, University of Washington, Seattle, WA, USA; Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, GA, USA; Department of Microbiology, University of Washington, Seattle, WA, USA; Department of Surgery, The Emory Transplant Center, Emory University School of Medicine, Atlanta, GA, USA; Tulane National Primate Research Center, Covington, LA, USA; Wisconsin National Primate Research Center, University of Wisconsin–Madison, WI, USA; Department of Population, Health and Reproduction, School of Veterinary Medicine, University of California–Davis, CA, USA; Division of Neuroscience, New England National Primate Research Center, Harvard Medical School, Southborough, MA, USA; National Primate Research Center Consortium, NyTech Strategic Planning, Clarendon Hills, IL, USA; Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX, USA |
| Abstract: | Abstract The National Primate Research Centers (NPRCs) established Working Groups (WGs) for developing resources and mechanisms to facilitate collaborations among non-human primate (NHP) researchers. Here we report the progress of the Genome Banking and the Genetics and Genomics WGs in developing resources to advance the exchange, analysis and comparison of NHP genetic and genomic data across the NPRCs. The Genome Banking WG has established a National NHP DNA bank comprising 1250 DNA samples from unrelated animals and family trios from the 10 NHP species housed within the NPRC system. The Genetics and Genomics WG is developing SNP arrays that will provide a uniform, highly informative, efficient and low-cost method for rhesus and long-tailed macaque genotyping across the eight NPRCs. This WG is also establishing a Biomedical Informatics Research Network-based portal for shared bioinformatics resources including vital statistics, genotype and population data and information on the National NHP DNA bank. |
| Keywords: | ancestry estimation Biomedical Information Research Network databases DNA bank genotype data information systems parentage testing population genetics single nucleotide polymorphisms web portal |