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Plasma membrane redox systems in tumor cells
Authors:M. A. Medina  I. Núñez de Castro
Affiliation:(1) Laboratorio de Bioquímica y Biología Molecular, Facultad de Ciencias, Universidad de Malaga, E-29071 Málaga, Spain
Abstract:Summary Plasma membrane redox systems in tumor cells are analyzed, their role in proton flux and tumor cell growth is described, and the modulation of their activity by antitumor drugs and growth factors is presented. As an example of the evolution of studies in the characterization of plasma membrane redox systems in tumor cells, we summarized our own results on the model system Ehrlich ascites carcinoma.
Keywords:Plasma membrane redox  Ferricyanide reductase  Ehrlich cells  Antitumor drugs
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