Abstract: | Electron microscopy applied in experiments on white mice has demonstrated the presence of vacuoles containing collagen fibers in the cytoplasm of hepatocytes during reverse development of liver cirrhosis. As the organ regenerated, the number of vacuoles with decomposing collagen in the hepatocytes and the number of phagocytosing hepatocytes increased. Based on the data obtained the conclusion is made that during reverse development of liver cirrhosis one can observe the phenomenon of intracellular resorption of collagen by hepatocytes by means of collagen phagocytosis. |