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纳米粒子-生物分子复合体的合成及其在生物医药领域的应用
引用本文:徐文涛,陈艳,陈伟,龙德鸿,杨旭石,沈鹤柏.纳米粒子-生物分子复合体的合成及其在生物医药领域的应用[J].现代生物医学进展,2007,7(8):1251-1255.
作者姓名:徐文涛  陈艳  陈伟  龙德鸿  杨旭石  沈鹤柏
作者单位:上海师范大学,上海,200234
摘    要:纳米粒子具有独特的光、电和催化性质;生物物质具有识别、催化和抑制的特性;纳米粒子连接生物分子从而合成了具有生物上的电、光性质的纳米粒子—生物分子复合体。本文介绍了纳米粒子-生物分子复合体系的合成,以及这些纳米粒子—生物分子复合体在生物医学领域的应用及研究进展。

关 键 词:纳米粒子  生物分子复合体  生物传感器  纳米生物技术  磁性分离
文章编号:1673-6273(2007)08-1251-05
修稿时间:2007-03-202007-04-12

The Synthesis of Integrated Nanoparticle-Biomolecule Hybrid Systems and Applications in the Bio-medical Field
XU Wen-tao,CHEN Yan,CHEN Wei,LONG De-hong,YANG Xu-shi,SHEN He-bai.The Synthesis of Integrated Nanoparticle-Biomolecule Hybrid Systems and Applications in the Bio-medical Field[J].Progress in Modern Biomedicine,2007,7(8):1251-1255.
Authors:XU Wen-tao  CHEN Yan  CHEN Wei  LONG De-hong  YANG Xu-shi  SHEN He-bai
Institution:Shanghai Normal University Shanghai 200234
Abstract:Nanopartides exhibit similar dimensions to those of biomolecules.Nanoparticles exhibit unique electronic,pho- tonic and catalytic properties,and biomaterials display unique discriminating,catalytic,and inhibitory properties.The integration of the two forms a novel hybrid material of synergetic properties and functions which called biomolecule-nanopanticle.This review outlines recent advances in synthesis of biomolecule-nanoparticle hybrid systems,and its application in the generation of 2D and 3D ordered structures in the solution or on the surfaces0],with emphasis on the use of biomolecule-nanoparticle(metallic or semi- conductive) assemblies for bioanalytical applications and for the fabrication of bioelectronic devices.
Keywords:Nanopartide  Hybrid Systems  Biosensors  Nanobiotechnology  Magnetic separation
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