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Towards immunotherapeutic drugs and vaccines against multiple sclerosis
Authors:Katsara Maria  Matsoukas John  Deraos George  Apostolopoulos Vasso
Institution:Burnet Institute, Austin Campus, Immunology and Vaccine Laboratory, Studley Road, Heidelberg, Victoria 3084, Australia;Department of Chemistry, Section of Organic Chemistry, Biochemistry, and Natural Products, University of Patras, Patras 26500, Greece
Abstract:Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system. Numerous treatment options are available to MS patients; however, these options need to be improved. Herein, we review the current drugs and therapeutic approaches available to MS patients, preclinical trial interventions and recent animal model studies for the potential therapy of MS. Since the current treatment of MS remains elusive and is limited, animal studies and clinical research offers an optimistic outlook.
Keywords:multiple sclerosis  MS treatment  immuno-suppressive drugs  immunomodulatory drugs  MS clinical trials  peptides  altered peptide ligand
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