Cloning and functional expression of a TEA-sensitive A-type potassium channel from rat brain. |
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| Authors: | K H Schr?ter J P Ruppersberg F Wunder J Rettig M Stocker O Pongs |
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| Affiliation: | Max-Planck-Institut für medizinische Forschung, Heidelberg, Germany. |
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| Abstract: | A rat brain cDNA (Raw3) related to the Drosophila Shaw K+ channel family has been characterized. Raw3 cRNA leads to the formation of TEA-insensitive, fast inactivating (A-type) K+ channels when injected into Xenopus laevis oocytes. Raw3 channels have markedly different properties from the previously cloned rat A-type K+ channel RCK4, Raw3 channels operate in the positive voltage range. |
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