Identification and complementation of a mutation associated with loss of Mycoplasma pneumoniae virulence-specific proteins B and C |
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| Authors: | Waldo Robert H Jordan Jarrat L Krause Duncan C |
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| Institution: | Department of Microbiology, 523 Biological Sciences Bldg., University of Georgia, Athens, GA 30602, USA. |
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| Abstract: | A mutation in gene MPN142 (orf6) was identified in the Mycoplasma pneumoniae cytadherence mutant III-4. MPN142 encodes virulence-specific proteins P90 and P40 (proteins B and C, respectively). Analysis of MPN142 in a cytadhering revertant and complementation using a recombinant wild-type allele confirmed the role of this mutation in the cytadherence defect. |
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