Protective activity of 28-kDa 1-Cys peroxiredoxin determines its peroxidase activity] |
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| Authors: | V I Novoselov I V Peshenko S V Novoselov S S Kamzalov M F Bystrova V A Evdokimov Iu V Nikolaev E E Fesenko |
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| Institution: | Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russia. |
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| Abstract: | The 28 kDa peroxiredoxin from rat exhibited peroxidase activity only in the presence of dithiothreitol. Both organic and nonorganic peroxidases were found to be substrates for the 28-kDa peroxiredoxin activity. Analysis of the protective antioxidant activity of the 28-kDa peroxiredoxin revealed that it is accounted for by its peroxidase activity. |
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