The flip side of synapse elimination |
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Authors: | Zito Karen |
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Affiliation: | Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA. |
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Abstract: | The fine tuning of synaptic circuits often requires an activity-dependent phase in which appropriate connections are strengthened and inappropriate connections are eliminated. In this issue of Neuron, Walsh and Lichtman propose a novel "synaptic takeover" mechanism for synapse elimination at the vertebrate NMJ, where withdrawal of one axon is accompanied by expansion of a competing axon into the newly vacated territory. |
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