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OpWise: Operons aid the identification of differentially expressed genes in bacterial microarray experiments |
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| Authors: | Morgan N Price Adam P Arkin Eric J Alm |
| Institution: | (1) Lawrence Berkeley Lab, , 1 Cyclotron Road, Mailstop 977-152, Berkeley, CA 94720, USA;(2) Virtual Institute of Microbial Stress and Survival, Berkeley, USA;(3) Howard Hughes Medical Institute, Berkeley, CA, USA;(4) Department of Bioengineering, University of California at Berkeley, Berkeley, CA, USA |
| Abstract: | BackgroundDifferentially expressed genes are typically identified by analyzing the variation between replicate measurements. These procedures implicitly assume that there are no systematic errors in the data even though several sources of systematic error are known. |
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