Sperm Cryopreservation in Male Infertility Due to Genetic Disorders |
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Authors: | Csilla Krausz Gianni Forti |
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Institution: | (1) Andrology Unit, Department of Clinical Physiopathology, Viale Pieraccini, 6, Firenze, Italy |
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Abstract: | Certain chromosomal and genetic anomalies, such as Klinefelter syndrome (47,XXY) and Y chromosome microdeletions, have been
reported as potential causes of a progressive impairment of spermatogenesis. In these cases cryoconservation of ejaculated
or testicular sperm represent a valuable tool for the preservation of fertility. However, dealing with genetic disorders,
the transmission of genetic anomalies has to be taken into consideration. It is therefore important to be aware about the
clinical importance and the related genetic risks of these anomalies. In this article we describe the clinical significance
of these diseases. |
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Keywords: | Cryopreservation Genetics Klinefelter syndrome Spermatogenesis Y chromosome |
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