Virucidal Nanofiber Textiles Based on Photosensitized Production of Singlet Oxygen |
| |
| Authors: | Yveta Lhotáková Luká? Plí?til Alena Morávková Pavel Kubát Kamil Lang Jitka Forstová Ji?í Mosinger |
| |
| Institution: | 1. Faculty of Sciences, Charles University in Prague, Prague, Czech Republic.; 2. Elmarco s.r.o., Liberec, Czech Republic.; 3. J.Heyrovský Institute of Physical Chemistry, v.v.i, Academy of Sciences of the Czech Republic, Prague, Czech Republic.; 4. Institute of Inorganic Chemistry, v.v.i, Academy of Sciences of the Czech Republic, Řež, Czech Republic.; Glasgow University, United Kingdom, |
| |
| Abstract: | Novel biomaterials based on hydrophilic polycaprolactone and polyurethane (Tecophilic®) nanofibers with an encapsulated 5,10,5,20-tetraphenylporphyrin photosensitizer were prepared by electrospinning. The doped nanofiber textiles efficiently photo-generate O2(1Δg), which oxidize external chemical and biological substrates/targets. Strong photo-virucidal effects toward non-enveloped polyomaviruses and enveloped baculoviruses were observed on the surface of these textiles. The photo-virucidal effect was confirmed by a decrease in virus infectivity. In contrast, no virucidal effect was detected in the absence of light and/or the encapsulated photosensitizer. |
| |
| Keywords: | |
|
|
