Quetzal: a transposon of the Tc1 family in the mosquito Anopheles albimanus |
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| Authors: | Zhaoxi Ke Genello L Grossman Anthony J Cornel Frank H Collins |
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| Institution: | (1) Division of Parasitic Diseases, Centers for Disease Control and Prevention, Chamblec, GA 30341, U.S.A.;(2) Biology Department, Emory University, 30322 Atlanta, GA, USA;(3) Present address: Department of Entomology, University of Georgia, 30602 Athens, GA, USA |
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| Abstract: | A member of the Tc1 family of transposable elements has been identified in the Central and South American mosquito Anopheles albimanus. The full-length Quetzal element is 1680 base pairs (bp) in length, possesses 236 bp inverted terminal repeats (ITRs), and has a single open reading frame (ORF) with the potential of encoding a 341-amino-acid (aa) protein that is similar to the transposases of other members of the Tc1 family, particularly elements described from three different Drosophila species. The approximately 10–12 copies per genome of Quetzal are found in the euchromatin of all three chromosomes of A. albimanus. One full-length clone, Que27, appears capable of encoding a complete transposase and may represent a functional copy of this element. |
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| Keywords: | culicidae gene vector transformation transposable element transposase |
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