Sister chromatid exchange in patients with viral disease |
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| Authors: | Karen Kurvink Clara D Bloomfield Jaroslav Cervenka |
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| Institution: | Division of Oral Pathology, University of Minnesota Health Sciences Center, Minneapolis 55455. |
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| Abstract: | Sister chromatid exchange (SCE) frequencies were studied in differentially stained chromosomes from lymphocytes of 17 patients with viral disease. The mean SCE score for the patients was 8.7 +/- 2.9 standard deviations. SCE scores were significantly elevated in the patients compared with the controls (p less than 0.01); however, variability in SCE means was observed in the patients. SCE elevations were also present in long term cultured Epstein Barr virus positive human B lymphocytes. |
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