Asymmetric syntheses of pipecolic acid and derivatives |
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Authors: | Dr François Couty |
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Institution: | (1) Laboratoire de synthèse asymétrique, Université Paris 6, 4, place Jussieu, F-75005 Paris, France |
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Abstract: | Summary Results in the field of asymmetric synthesis of pipecolic acid derivatives are reviewed. Three sections describe the asymmetric syntheses of the title compounds (i) from the chiral pool (-amino acids or carbohydrates) (ii) using a chiral auxiliary either derived from terpenes,-amino acids, tartaric acid, an amine or-amino alcohols (iii) by means of asymmetric catalysis. |
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Keywords: | Amino acids Pipecolic acid Pipecolic acid derivatives Asymmetric synthesis Hemisyntheses Chiral auxiliaries |
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