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Rotaviruses in younger children in Novosibirsk in 2005-2007: detection and genotyping
Authors:Zhirakovskaia E V  Maleev V V  Klemesheva V V  Bodnev S A  Korsakova T G  Tikunov A Iu  Iun T E  Nikiforova N A  Netesov S V  Tikunova N V
Abstract:Examination of 1898 patients with acute enteric infection from March 2005 to February 2007 showed that group A rotaviruses were the most frequent cause (35%) of acute gastroenteritis among children under 3 years of age. Majority of cases of rotavirus infection was detected in infants under 1 year of age (71.8%). The peak of sporadic incidence was observed between February and May. High rate of mixed infection (45.6%) was observed - associations of rotaviruses with other viruses (noroviruses, astroviruses) and bacteria (Salmonella, Shigella, enteroinvasive Escherichia coli, Campylobacter, and opportunistic species) were detected. P- and G-genotypes of 337(50.8%) isolates of group A rotaviruses were determined by RT-PCR. The most prevalent strain was P8]G1 (54.6%) followed by P8]G3 (10.7%), P8]G9 (8.6%), P4]G2 (8.3%), and P8]G4 (4.5%) genotypes.
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