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Persistence with anti-tumour necrosis factor therapies in patients with psoriatic arthritis: observational study from the British Society of Rheumatology Biologics Register |
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| Authors: | Amr A Saad Darren M Ashcroft Kath D Watson Kimme L Hyrich Peter R Noyce Deborah PM Symmons the British Society for Rheumatology Biologics Register |
| Affiliation: | (1) School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK;(2) Arthritis Research Campaign Epidemiology Unit, University of Manchester, Oxford Road, Manchester, M13 9PT, UK |
| Abstract: | IntroductionAnti-TNF therapies represent a breakthrough in the treatment of severe psoriatic arthritis. However, little is known about long-term drug persistence with these treatments in patients with psoriatic arthritis in routine clinical practice. The aim of this study was to assess persistence with first-course and second-course treatment with anti-TNF agents in a prospective cohort of psoriatic arthritis patients and to identify factors associated with and reasons for drug discontinuation. |
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