Effect of exposure to high temperatures in the excretion of cadmium and lead |
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Affiliation: | 1. Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA;2. Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA;1. Felsenstein Medical Research Center, Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv, Israel;2. Dep. of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv, Israel;3. Medicine A, Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv, Israel;4. Unit of Infectious Diseases, Sheba Medical Center, Tel-Hashomer, Israel;5. Endocrinology Laboratory, Beilinson Medical Center, Petah-Tikva, Israel |
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Abstract: | ObjectiveThis study aims to observe the effect on urine and sweat excretion levels of cadmium (Cd) and lead (Pb) in healthy men in a maximum incremental test until exhaustion and repeated exposure to heat.Methodstwenty-nine adult men divided into control group (CG; n = 14) and experimental group (EG; n = 15) performing two maximum tests until exhaustion in normothermia (22 °C) and hyperthermia (42 °C). EG experienced 9 sessions of heat exposure at high temperatures (100 °C) (HEHT). After the nine sessions, the initial tests were repeated in both groups. Urine samples were collected before and after each test. After the hyperthermia tests, sweat samples were gathered.ResultsUrinary Cd increased after initial tests in GC and in hyperthermia in EG (p < 0.05). Urinary excretion of Pb rose after HEHT (p < 0.05). Pb in sweat was higher in EG than in CG after HEHT (p < 0.05).ConclusionHeat exercise and constant exposure to heat can be a valid method to increase the excretion of toxic metals. |
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