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Chemical constituents from Ailanthus altissima (Mill.) Swingle and chemotaxonomic significance
Affiliation:1. Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, China;2. Engineering Research Center of Natural Medicine Active Molecule Research & Development, Liaoning Province, China;3. Key Laboratory of Natural Bioactive Compounds Discovery & Modification, Shenyang, China;4. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, China;1. College of Pharmacy, Kyung Hee University, Seoul 130-701, Republic of Korea;2. Department of Life & Nanopharmaceutical Science, Kyung Hee University, Seoul 130-701, Republic of Korea;3. Central Research Institute, Whan In Pharm Co., Ltd, Suwon 443-766, Republic of Korea
Abstract:Sixteen compounds were isolated from the root barks of Ailanthus altissima (Mill.) Swingle, including thirteen lignans (113), two coumarins (1415), and one chalcone (16). This is the first report on the occurrence of compounds 116 in the genus Ailanthus. Their structures were elucidated on the basis of NMR spectroscopic data. The plant distribution network of all isolated compounds was described to illustrate the significance of taxonomy. The presence of these congenetic lignans (113) and their biosynthetic relationships may be used for identification of Ailanthus genus.
Keywords:Lignans  Coumarins  Chemotaxonomic significance
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