Orienting the Direction of EGFR Activation |
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| Authors: | Ben-Zion Shilo Eyal D Schejter |
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| Institution: | Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel. |
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| Abstract: | Morphogens are typically distributed symmetrically from their source of production. In this issue of Developmental Cell, Peng et?al. (2012) demonstrate that a bias in the directionality of protrusions emanating from cells secreting the EGFR ligand Spitz leads to asymmetric activation of the pathway. |
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