| 耐药机制指导下的抗金葡菌药物开发现状 |
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| 引用本文： | 杨杰,饶贤才.耐药机制指导下的抗金葡菌药物开发现状[J].微生物学杂志,2007,27(3):83-86. |
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| 作者姓名： | 杨杰 饶贤才 |
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| 作者单位： | 第三军医大学,微生物学教研室,重庆市微生物工程重点实验室,重庆,400038 |
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| 摘 要： | 金黄色葡萄球菌是全球院内感染的首要病原菌,临床分离的金葡菌80%以上为耐甲氧西林(MRSA)菌株,因其耐药性,尤其是多重耐药性的快速增长,抗MRSA感染日益成为抗感染治疗的难点和热点。近年来,人们在充分认识金葡菌耐药机制的基础上,积极开发新型抗MRSA药物,取得了长足发展。对MRSA的耐药机制及该机制指导下抗金葡菌药物开发现状作一综述。
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| 关 键 词： | 耐药性 药物 |
| 文章编号： | 1005-7021(2007)03-0083-04 |
| 修稿时间： | 2006年9月25日 |
Current Development of Anti-Staphyloccus aureus Medicine under the Guidance of Mechanism of Drug Resistance |
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| YANG Jie,RAO Xian-cai.Current Development of Anti-Staphyloccus aureus Medicine under the Guidance of Mechanism of Drug Resistance[J].Journal of Microbiology,2007,27(3):83-86. |
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| Authors: | YANG Jie RAO Xian-cai |
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| Abstract: | Staphyloccus aureus(SA) is one of the primary pathogenic bacteria in global hospital infections.More than 80% of clinically isolated SA are methicillin-resistant ones(MRSA),since its medicine resistance,especially the fast growth of multi-drug resistance of SA has made anti-MRSA infection becoming difficulty and hot spot of anti-infection treatment.Recently,based on people's full knowledge about the mechanism of SA's drug resistance,new medicine of anti-MRSA has been positively developed and got rapid growth.Current development of MRSA drug resistance mechanism and anti-SA medicine under the guidance of the mechanism of drug resistance was reviewed in this article. |
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| Keywords: | MRSA |
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