Is cadmium released from metallothionein in rejected human kidneys? |
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Authors: | Carl-Gustaf Elindert Monica Nordberge Brita Palm |
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Institution: | (1) Departments of Renal Medicine and Transplantation Surgery, Huddinge Hospital, Karolinska Institutet, S-14186 Huddinge, Sweden;(2) Department of Environmental Hygiene, Karolinska Institutet, S-10401 Stockholm, Sweden |
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Abstract: | Summary Concentrations of metallothionein and metals, i.e. cadmium, copper and zinc, were determined in six rejected transplanted human kidneys and one kidney prepared for transplantation. Tissue samples separated by gel chromatography showed that almost all of cadmium in tissue was in the form of firmly bound cadmium-metallothionein. |
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Keywords: | Kidney Metals Metallothionein Rejection Transplantation |
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