Mannic acid,a new ent-kaurane dimer diterpenoid and other chemical constituents from different parts of Diospyros mannii |
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| Institution: | 1. Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China;2. School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong 999077, China;3. School of Stomatology and Medicine, Foshan University, Foshan 528000, China;4. School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, China;5. Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen 518057, China |
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| Abstract: | A new dimeric ent-kaurane diterpene, mannic acid (1), and 19 known compounds were isolated from the methanol extract of the stems, roots and leaves of Diospyros mannii Hiern (Ebenaceae). Their structures were established by NMR and MS data. This is the first report of asperglaucide from the family Ebenaceae, while mannic acid (1) and xylopic acid (2) are the first ent-kaurane diterpenes isolated from this family. Their chemotaxonomic value is discussed. |
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| Keywords: | Ebenaceae Kaurane diterpene Mannic acid Chemotaxonomic value |
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