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Chemotaxonomic importance of diarylheptanoids and phenylpropanoids in Saxifraga tangutica (Saxifragaceae)
Affiliation:1. Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, PR China;2. Shaanxi Key Laboratory of Bio-Resources, Shaanxi University of Technology, Hanzhong, Shaanxi, PR China;1. Institute of Chemistry, Department of Organic Chemistry, São Paulo State University – UNESP, Araraquara, SP, Brazil;2. Agronomic Institute of Campinas, Herbarium IAC, Campinas, SP, Brazil;1. Weinan Central Hospital, Shengli Rd, Weinan, 714000, PR China;2. Shaanxi University of Chinese Medicine, Western Century Avenue, Xianyang, 712046, PR China;1. State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China;2. School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China;3. Department of Medicinal Chemistry & Pharmacognosy (MC 781), UIC College of Pharmacy, Chicago, IL 60612-7231, USA;1. Department of Biology, Faculty of Science, Azarbaijan Shahid Madani University, Tabriz, Iran;2. Mycobacteriology Research Centre (MRC), National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran;3. Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran;4. Technical and Engineering Campus of Shahid Beheshti University, Tehran, Iran;5. Phytochemical Laboratory, Department of Chemistry, Faculty of Sciences, Azarbaijan Shahid Madani University, Tabriz 53714-161, Iran
Abstract:A phytochemical investigation of Saxifraga tangutica led to the isolation of 11 compounds, including eight diarylheptanoids (16, 10 and 11) and three phenylpropanoids (79). The chemical structures were established by extensive analysis of their MS and NMR spectroscopic data or comparison with literature data. In the present research, we report the isolated compounds 111, for the first time, in the species S. tangutica. Moreover, compounds 1, 2 and 411 have not been reported from any species in Saxifragaceae family. Furthermore, we discuss the chemotaxonomic significance of the isolated compounds.
Keywords:Saxifragaceae  Diarylheptanoids  Phenylpropanoids
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