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The Preprotein Binding Domain of SecA Displays Intrinsic Rotational Dynamics
Authors:Niels Vandenberk  Spyridoula Karamanou  Athina G Portaliou  Valentina Zorzini  Johan Hofkens  Jelle Hendrix  Anastassios Economou
Institution:1. KU Leuven, Department of Chemistry, Division for Molecular Imaging and Photonics, Laboratory for Photochemistry and Spectroscopy, Celestijnenlaan 200F, B-3001 Leuven, Belgium;2. KU Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory for Molecular Bacteriology, Herestraat 49, Gasthuisberg Campus, B-3000 Leuven, Belgium;3. Dynamic Bioimaging Lab, Advanced Optical Microscopy Centre, Biomedical Research Institute, Agoralaan C (BIOMED), Hasselt University, B-3590 Diepenbeek, Belgium
Abstract:
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  • Keywords:single-molecule Förster resonance energy transfer  pulsed interleaved excitation  protein conformational dynamics  photon distribution analysis  bacterial secretion pathway  SecA motor ATPase  PBD domain motions
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