| 刺激中缝背核不同区域对颏舌肌和膈肌的影响 |
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| 作者姓名： | Yu P Song G Liu L Liu YX |
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| 作者单位： | 1. 山东医科大学基础医学院生理教研室,济南,250012
2. 山东医科大学基础医学院机能中心实验室,济南,250012 |
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| 摘 要： | 本实验在４８只氨基甲酸惭酯麻醉、断双侧迷走神经的健康家兔上观察了电、化学刺激中缝背核背侧区（ｄＮＲＤ）和腹侧区（ｖＮＲＤ）对颏舌肌和膈肌肌电积分活动的影响。结果如下：（１）长串电脉冲刺激ｄＮＲＤ使颏舌肌和膈肌肌电活动均明显增强;（２）长串电脉冲刺激ｖＮＲＤ时,颏舌肌活动被易化,而膈肌活动则被抑制;（３）在ｄＮＲＤ和ｖＮＲＤ分别微量注射谷氨酸钠,其效应与电刺激结果基本一致。结果提示：（３）在ｄＮＲＤ
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| 关 键 词： | 中缝背核 颏舌肌 膈肌 上呼吸阻力 |
| 修稿时间： | 1996年11月22 |
Effects of stimulation at different areas of nucleus raphe dorsalis on genioglossus and diaphragm activities |
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| Yu P,Song G,Liu L,Liu YX.Effects of stimulation at different areas of nucleus raphe dorsalis on genioglossus and diaphragm activities[J].Acta Physiologica Sinica,1998,50(1):106-110. |
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| Authors: | Yu P Song G Liu L Liu Y X |
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| Institution: | Department of Physiology, Shangdong Medical University, Jinan 250012. |
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| Abstract: | Effects of electrical and chemical stimulation of the dorsal and ventral areas of the nucleus raphe dorslis(dNRD and vNRD)on genioglossus and diaphragm activities were observed in 48 urethan-anasthetized and vagotomized raddits.(1)Long train electrical stimulation at the dNRD facilitated genioglossus and diaphragm activities.(2)Long train electrical stimulation delivered to the vNRD excited genioglOssus activity but inhibited diaphragm activity.(3)Effects of microinjection of glutamate at the dNRD and vNRD were simillar to the effects of electrical stimulation.The above results suggest that excitation of nucleus raphe dorsalis(NRD)increases genioglossus activity and reduces upper airway resistance.The dNRD and vNRD play different roles in modulating diaphragm activity. |
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| Keywords: | nucleus raphe dorsalis genioglossus diaphragm upper airway resistance |
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