Association Between Antioxidant Intake/Status and Obesity: a Systematic Review of Observational Studies |
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| Authors: | Banafshe Hosseini Ahmad Saedisomeolia |
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| Affiliation: | 1.School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine,University of Newcastle,Callaghan,Australia;2.Department of Pharmacy, School of Medicine,Western Sydney University,Richmond,Australia;3.School of Molecular Bioscience,University of Sydney,Sydney,Australia;4.School of Medicine, Campbelltown Campus,Western Sydney University,Richmond,Australia |
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| Abstract: | The global prevalence of obesity has doubled in recent decades. Compelling evidences indicated that obesity was associated with lower concentrations of specific antioxidants which may play a role in the development of obesity-related diseases such as cardiovascular disease. The present review aimed to synthesize the evidence from studies on the association between obesity and antioxidant micronutrients in a systematic manner. Data bases including MEDLINE, Science Direct, and Cochrane were searched from inception to October 2015. Thirty-one articles were reviewed using the MOOSE checklist. Lower concentrations of antioxidants have been reported in obese individuals among age groups worldwide. Circulatory levels of carotenoids, vitamins E and C, as well as zinc, magnesium, and selenium were inversely correlated with obesity and body fat mass. However, studies demonstrated inconsistencies in findings. Lower status of carotenoids, vitamins E and C, zinc, magnesium, and selenium appears to be associated with adiposity. Intervention studies may be needed to establish the causality of these associations. |
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