Improved methodologies for the study of adipose biology: insights gained and opportunities ahead |
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| Authors: | Qiong A Wang Philipp E Scherer Rana K Gupta |
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| Institution: | *Department of Internal Medicine, Touchstone Diabetes Center, and University of Texas Southwestern Medical Center, Dallas, TX, 75287;†Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75287 |
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| Abstract: | Adipocyte differentiation and function have become areas of intense focus in the field of energy metabolism; however, understanding the role of specific genes in the establishment and maintenance of fat cell function can be challenging and complex. In this review, we offer practical guidelines for the study of adipocyte development and function. We discuss improved cellular and genetic systems for the study of adipose biology and highlight recent insights gained from these new approaches. |
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| Keywords: | energy metabolism adipogenesis obesity |
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