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1,3-Disubstituted-imidazo[1,5-a]pyrazines as insulin-like growth-factor-I receptor (IGF-IR) inhibitors |
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| Authors: | Mulvihill Mark J Ji Qun-Sheng Werner Doug Beck Patricia Cesario Cara Cooke Andrew Cox Matthew Crew Andrew Dong Hanqing Feng Lixin Foreman K W Mak Gilda Nigro Anthony O'Connor Matthew Saroglou Lydia Stolz Kathryn M Sujka Izabela Volk Brian Weng Qinghua Wilkes Robin |
| Affiliation: | (OSI) Oncology, OSI Pharmaceuticals, Inc., 1 Bioscience Park Drive, Farmingdale, NY 11735, USA. mmulvihill@osip.com |
| Abstract: | A series of novel 8-amino-1,3-disubstituted-imidazo[1,5-a]pyrazines was designed and synthesized as IGF-IR inhibitors. |
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