A new molecular evolution model for limited insertion independent of substitution |
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Authors: | Sophie Lè bre,Christian J. Michel |
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Affiliation: | Equipe de Bioinformatique Théorique, BFO, ICube, Université de Strasbourg, CNRS, 300 Boulevard Sébastien Brant, 67400 Illkirch, France |
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Abstract: | We recently introduced a new molecular evolution model called the IDIS model for Insertion Deletion Independent of Substitution and . In the IDIS model, the three independent processes of substitution, insertion and deletion of residues have constant rates. In order to control the genome expansion during evolution, we generalize here the IDIS model by introducing an insertion rate which decreases when the sequence grows and tends to 0 for a maximum sequence length nmax. |
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Keywords: | Evolution models Substitution Limited insertion Sequence length Sequence content GC content |
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