Dominant lethal mutations in Tilapia mossambica (Peters) elicited by myleran |
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| Affiliation: | 1. Graduate School of Regional Innovation Studies, Mie University, Tsu, Mie 514-8507, Japan;2. Mie University Zebrafish Drug Screening Center, Tsu, Mie 514-8507, Japan;3. Department of Integrative Pharmacology, Mie University Graduate School of Medicine, Tsu, Mie 514-8507, Japan;4. Department of Bioinformatics, Mie University Advanced Science Research Promotion Center, Tsu, Mie 514-8507, Japan;1. College of Environment and Plant Protection, Hainan University, Haikou 570228, China;2. Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, Honolulu, HI 96822, USA |
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| Abstract: | Tilapia mossambica (Peters) Teleostei, Cichlidae, is of commercial importance being farmed for human consumption. An effective means of sterilization would be of value since prolific breeding under farming conditions reduces growth rate. The possibility of using the antileukaemic drug myleran as a chemosterilant has been investigated previously, however the present study indicated that it can induce dominant lethal mutations in this species. |
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