FTLD-TDP with motor neuron disease,visuospatial impairment and a progressive supranuclear palsy-like syndrome: broadening the clinical phenotype of TDP-43 proteinopathies. A report of three cases期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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FTLD-TDP with motor neuron disease,visuospatial impairment and a progressive supranuclear palsy-like syndrome: broadening the clinical phenotype of TDP-43 proteinopathies. A report of three cases

Authors:	Robert Rusina Gabor G Kovacs Jind?ich Fiala Jakub Hort Petr Ridzoň Iva Holmerová Thomas Ströbel Radoslav Matěj

Institution:	(1) Department of Neurology, Thomayer Teaching Hospital and Institute for Postgraduate Education in Medicine, Prague, Czech Republic;(2) Institute of Neurology, Medical University of Vienna, Vienna, Austria;(3) Department of Neurology, Charles University, 2nd Medical Faculty and Motol Teaching Hospital, Prague, Czech Republic;(4) International Clinical Research Center, Brno, Czech Republic;(5) Centre of Gerontology and Faculty of Humanity Studies, Charles University in Prague, Prague, Czech Republic;(6) Department of Pathology and Molecular Medicine, Thomayer Teaching Hospital, Prague, Czech Republic;(7) Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic

Abstract:	Background Frontotemporal lobar degeneration with ubiquitin and TDP-43 positive neuronal inclusions represents a novel entity (FTLD-TDP) that may be associated with motor neuron disease (FTLD-MND); involvement of extrapyramidal and other systems has also been reported.

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