低龄婴幼儿龋微生物群落的研究进展

低龄婴幼儿龋(early childhood caries,ECC)是影响全世界儿童最常见的疾病之一,然而龋病并不是由单一致龋细菌引起,而是由微生物、宿主、饮食和时间,即"龋病病因四因素"之间复杂的相互作用所引起,其中微生物因素起着主要作用。口腔微生物之间存在着一种稳定关系,与宿主保持着和谐的生态平衡,一旦受到某种特殊环境改变的影响,这种平衡则可能被打破。到目前为止,国内外关于ECC的微生物群落研究方法很多,结果不尽相同,因此了解ECC的组成及动态变化对于儿童龋病的预防和防治极其重要。本文就ECC微生物群落的研究进展作一详细综述。

The microbial communities of early childhood caries: Research progress

Abstract: Early childhood caries (ECCs) are one of the most common diseases affecting children all over the world. The cause of caries is not the development of a single cariogenic bacteria, but the complex interactions between microbes, hosts, diet and time, i.e. the four factors of the cause of caries, in which microbial factor plays a major role. There is a stable relationship between oral microbes, which maintains a harmonious ecological balance between microbes and the host. The balance may be broken once it is changed by a particular environment. So far, there are many research methods on microbial communities of caries in early childhood at home and abroad, and the results are different. Therefore, understanding the composition and dynamic changes of ECC pathogens in young children is important for the prevention and control of caries in children. This article will give a detailed review on the progress in research on the microbial community of infants and young children.