微生态制剂防治儿童感染性腹泻的有效性评价

目的 对微生态制剂防治儿童感染性腹泻的有效性和安全性进行分析研究。方法 选取2017年3月到2018年3月间我院收治的132例感染性腹泻患儿为研究对象，依据随机数字表法分为对照组（n=66）与观察组（n=66）。对照组患儿施以常规药物防治，观察组患儿应用益生菌进行防治。对两组患者的治疗效果、腹泻持续时间、治疗后病情、血常规与肝功能情况进行比较分析。结果 观察组患儿治疗总有效率（96.97%）明显高于对照组（86.36%）。观察组患儿腹泻持续时间为（2.41±1.08）d，明显少于对照组的（3.67±1.89）d。观察组患儿治疗3 d后腹泻频率≤2次/d的发生率为24.24%，低于对照组的60.61%。观察组患儿治疗后脱水发生率为3.03%，低于对照组的22.73%。观察组患儿血常规与肝功能水平明显高于对照组，差异均有统计学意义（P＜0.05）。结论 在儿童感染性腹泻中应用微生态制剂有助于提高治疗效果，缩短腹泻持续时间，促进大便恢复正常，且具有较高的安全性，可有效促进患儿康复。

Evaluation of the effectiveness of microecological preparations in the prevention and treatment of infectious diarrhea in children

Objective To analyze the effectiveness and safety of microecological preparations in the prevention and treatment of infectious diarrhea in children. Methods 132 children with infectious diarrhea in our hospital from March 2017 to March 2018 were enrolled and randomly divided into control group (n=66) or observation group (n=66). The control group was treated with conventional drugs while the observation group was treated with probiotics. The therapeutic effect, duration of diarrhea, condition after treatment, routine blood test and liver function were compared between the two groups. Results The total efficiency rate in observation group was higher than in control group (96.97% vs 86.36%, P<0.05). The duration of diarrhea in the observation group was (2.41±1.08) days, less than the (3.67±1.89) days in the control group. After 3 days of treatment, The incidence of diarrhea frequency ≤ 2 times / d after treatment for 3 days in the observation group was 24.24%, lower than that in control group (60.61%). The incidence of dehydration in the observation group (3.03%) was lower than that in control group (22.73%). The blood routine and liver function in observation group were significantly better than in the control group (Ps<0.05). Conclusion The application of microecological probiotics in children with infectious diarrhea can improve the therapeutic effect, shorten the duration of diarrhea and promote the restore of normal stools with high safety, which can effectively promote the rehabilitation of children.