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Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction

Authors:	Hallows William C Yu Wei Smith Brian C Devries Mark K Devires Mark K Ellinger James J Someya Shinichi Shortreed Michael R Prolla Tomas Markley John L Smith Lloyd M Zhao Shimin Guan Kun-Liang Denu John M

Institution:	Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI 53706, USA.

Abstract:	Download : Download high-res image (176KB) Download : Download full-size image Highlights? High-throughput analyses identify potential targets of Sirt3 ? Sirt3 deacetylates and stimulates ornithine transcarbamoylase ? Caloric restriction induces Sirt3 expression and stimulation of the urea cycle ? Sirt3 regulates amino acid catabolism and β-oxidation during caloric restriction

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