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Crystal structures of the Streptomyces coelicolor TetR-like protein ActR alone and in complex with actinorhodin or the actinorhodin biosynthetic precursor (S)-DNPA
Authors:Willems A R  Tahlan K  Taguchi T  Zhang K  Lee Z Z  Ichinose K  Junop M S  Nodwell J R
Institution:1 Department of Biochemistry and Biomedical Sciences, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada L8N 3Z5
2 Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo 202-8585, Japan
Abstract:
Keywords:(S)-DNPA  4-dihydro-9-hydroxy-1-methyl-10-oxo-3-H-naphtho-[2  3-c]-pyran-3-(S)-acetic acid  DBD  DNA-binding domain  LBD  ligand-binding domain  SeMet  selenomethionine  PEG  polyethylene glycol  PDB  Protein Data Bank
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