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Metabolism of lysine-chromium complex in Saccharomyces cerevisiae
Authors:K S Karthikeyan  H Polasa  K Sivarama Sastry  Gopal Reddy
Institution:(1) Department of Microbiology Osmania University, Hyderabad, 500 007, India
Abstract:Saccharomyces cerevisiae which cannot utilize lysine as a sole nitrogen source is shown to metabolize a Lysine 3 Cr3+ (1:1) complex synthesized, as a combined nitrogen and carbon source. It induces rapid uptake of lysine and prevents loss of viability, in contrast with free lysine. That complexation with trivalent chromium has the effect of profoundly influencing intracellular distribution and metabolism of the liganded amino acid is demonstrated.
Keywords:Saccharomyces cerevisiae            Lysine  Lysine-chromium complex  Metabolism
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